- In a biological neural network: neurons in a biological neural network fire when and if they receive enough stimulus via their (input) synapses. This means that an electrical impulse is propagated along the neuron's axon and transmitted to other neurons via the output synaptic connections of the neuron. The firing rate of a neuron is the frequency with which it fires (cf. activation in an artificial neural network.
- In an expert system: when a rule in the expert system is used, it is said to fire.
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